A Mother's Mission, A Son's Strength: Fighting for Sickle Cell Warriors

As Executive Director of Sickle Cell Warriors of Buffalo, Melaney Agahiu’s mission is to educate and advocate for Sickle Cell Warriors across the community.

“Unfortunately, a lot of people turn a blind eye when they, unless it hits home. It’s easy to just ignore. I challenge people to learn about sickle cell and how it impacts people, and how they can help.”

For Melaney, that challenge is especially personal. Her son, 18-year-old Drew Agahiu, is a warrior himself.

“Initially, I was coming into Sickle Cell Warriors of Buffalo for support. Then it turned into a lot of volunteering. Sometimes it’s just being able to talk to someone who just gets it.”

Sickle cell disease is the most common genetic blood disorder in the United States, and it’s estimated that more than 100,000 people have sickle cell nationwide. Sickle cell disease distorts soft, round blood cells, turning them hard and crescent-shaped, which can lead to severe pain, tissue and organ failure, anemia, infections and strokes.

Throughout their journey, Drew and Melaney have been fortunate to be surrounded by a large community of supporters each making an impact, from family, friends, their Sickle Cell Warriors of Buffalo family – and a community of strangers nationwide.

“It means a lot to me,” Drew explained. “I feel like blood donors give a lot of support to me. Actually, they give 100 percent support to me. It’s hard to put into words.”

For warriors like Drew, regular blood and platelet transfusions are critical to managing extreme pain and life-threatening complications caused by sickle cell. After receiving multiple transfusions over the course of his treatment, Drew began receiving monthly apheresis transfusions two years ago.

“If it weren’t for people donating blood, Drew would probably be in a much worse condition,” Melaney said. “Before that, it was 6 or 7 hospital admissions a year. You know, it would be maybe 5 days to, you know, 6 to 8 weeks that he would be in the hospital, and that would include a handful of ICU admissions. Now, he probably has one hospital admission a year, maybe. It’s a blessing. He still obviously experiences pain and has crises, but oftentimes we can manage it at home, and I know for a fact that’s because of the transfusions.”

Noting her son’s extra energy as a result, Drew was quick to agree with a smile. 

“Now that we’ve been doing it once a month, that’s been a big change for me and it’s helping with my pain.”

That’s why Melaney says her work challenging the public to educate themselves on sickle cell is doubly important.  

Transfusions rely heavily on donors who carry CEK-negative antigens, which provides the best blood match and helps alleviate symptoms for those fighting sickle cell. Blood donors who are African American are nearly three times more likely to be CEK-negative than donors of a different race or ethnicity.

“Why is it important for people to donate blood?” Melaney asked. “It’s because it saved his life and other Sickle Cell Warriors. I can speak firsthand. I see the night and day.”

Drew agreed, “Don’t be afraid. You’re the biggest help to sickle cell warriors. Your support helps me to be there to hang out with friends or enjoy special moments.”

As our nation observes Juneteenth and World Sickle Cell Day on Friday, June 19, the Red Cross is honoring sickle cell warriors like Drew, the light they carry and the community of blood donors who surround them.

Every donation helps patients continue to thrive. The Red Cross encourages eligible donors of all backgrounds to make an appointment to give blood and help ensure patients with sickle cell disease have access to the lifesaving transfusions they need.

Those who come to give blood June 1-28, 2026, will receive a $15 e-gift card to a merchant of choice and be automatically entered for a chance to win one of two $7,500 gift cards.

Make an appointment to donate by visiting RedCrossBlood.org, calling 1-800-RED CROSS or using the Red Cross Blood Donor App.

Written by: Meg Rossman, American Red Cross of WNY

"It was a chain-reaction:" How blood donation led a local health care advocate to support Sickle Cell warriors in need

From a young age, Jasmine Westbrook understood the importance of blood donation.

“The first time I was introduced to donating blood I was in high school. We had a drive, but you know, when you’re in high school, you don’t have the best diet – especially breakfast. You’re not eating right, so a majority of us, myself included, couldn’t donate,” she laughed. “I initially donated blood about 10 years ago in college during a drive and I was a little bit more educated on having a balanced meal the night before and before the donation.”

She credits her mother, a longtime blood donor herself, for inspiring her to set a routine early on in life.

“We just want to do good,” Westbook explains. “In the last five years, I’ve started donating regularly once I really understood what my blood donation could do. How it could really impact somebody. I was doing it because I knew it would help people.”

But it was after Westbrook attended a panel discussion on Sickle Cell Disease co-hosted by Sickle Cell Warriors of Buffalo, the American Red Cross of Western New York and community partners that she began to look at her role as a blood donor in a new light.

“I attended and I really learned about the CEK-negative component.”

There are an estimated 100,000 people suffering from the effects of Sickle Cell disease in the United States. From pain to organ failure, patients with Sickle Cell often face serious medical complications due to an inherited gene that creates sickle-shaped red blood cells, causing difficulty in navigating through small blood vessels. As a result, blood transfusions are vital to treatment, with some patients requiring approximately 100 transfusions per year.

Transfusions rely heavily on donors who carry CEK-negative antigens, which provides the best blood match and helps alleviate symptoms for those fighting Sickle Cell. Blood donors who are African American are nearly three times more likely to be CEK-negative than donors of a different race or ethnicity.

To help increase the availability of close-matching blood for Sickle Cell patients, the American Red Cross launched the Sickle Cell Initiative in 2021. Since the launch, more than 125,000 first-time African American donors have rolled up a sleeve to help strengthen and diversify the blood supply. And as part of that initiative, more than 260,000 Sickle Cell trait screenings have been provided to donors.

“I left that event and wanted to know if I had that protein, because people talk about blood types, but they don’t always talk about that,” Westbrook says. “That day, I donated double reds, they tested it, and I got the card was told I was CEK-negative.”

Since then, Westbrook’s personal and professional motivations to encourage others to roll up a sleeve have taken on new meaning. A health care advocate with the Healthcare Education Project, Westbrook works directly with patients and the public through community events and uses the opportunity to inspire and educate others to donate not only for themselves but patients – especially Sickle Cell Warriors in need.

“I feel like it’s my duty because I have a protein in my blood that allows me to really help people and specifically in the African American community. A lot of the work that I do is coming back to my cultural group and knowing that I have the protein in my blood – that will really help people with sickle cell, which is an illness that is high in our community. Of course, I’ll share my blood. A big part of my role is advocacy on a statewide level for access to health care. I’m able to share information with people to help keep our community more educated, like with Sickle Cell. When the conversation comes up now, I’m equipped with information to say, ‘Why don’t you donate and see if you have that protein?’ I’m helping to pass the word around so we can have a healthier community. So, it’s personal for me and its business.”

You can learn more and help give to patients in need by making an appointment to donate at RedCrossBlood.org, by calling 1-800 RED CROSS (1-800-733-2767) or by downloading the free Red Cross Blood Donor app to your smartphone.

Meg Rossman, Regional Communications Manager, American Red Cross of Western New York